Does the site function as expected when Shields are turned off?
Yes
Is there a specific Shields configuration that causes the site to break? If so, tell us that configuration. (yes/no):
I tried turning off everything and Twitter still doesn’t load. I have to turn shield off completely to get it to load.
Does the site work as expected when using Chrome?
No idea.
Brave version (check About Brave):
Version 1.5.112 Chromium: 80.0.3987.132 (Official Build) (64-bit)
If twitter works in a new profile, that means there is something with your main profile that is preventing twitter from loading. We’ll have to go through some steps to rest things.
Can you go to twitter and make sure your Shield settings matches mine in this picture:
Enter this link to your address bar: brave://settings/content/siteDetails?site=https%3A%2F%2Ftwitter.com
then click on clear data and reset permissions
Revisit twitter and let me know if things load properly. If it’s not loading properly you might have an extension causing the issue, you can try disabling them to see if twitter will load.