Hi brave,
Firstly, congrats on a very good browser.
I have come from google chrome because they continually reduce what the user can customise.
However, I still use Gmail as my email client combined with default settings, Ublock Origin. It all works, now given your browser is security centric, I think with some advice, I should be able to achieve the same with your inbuilt security.
Linux Manjaro
Bave Ver: 1.66.118 Chromium: 125.0.6422.147 (64-bit)
Here are my settings:-
All responses appreciated